Intravenous Anæsthesia with Special Reference to the Use of the Barbiturates

Intravenous Anæsthesia with Evipan Sodium in Children

Evipan sodium is a barbiturate derivative of lengthy formula. The drug injected intravenously produces a general anaesthesia, which is of short duration owing to rapid detoxication by the liver, so lending itself to minor operations and short manipulations. The therapeutic index-the ratio between the minimum therapeutic dose and the minimum lethal dose-is 5, higher than that of any other barbit...

QSAR models to predict physico-chemical Properties of some barbiturate derivatives using molecular descriptors and genetic algorithm- multiple linear regressions

In this study the relationship between choosing appropriate descriptors by genetic algorithm to the Polarizability (POL), Molar Refractivity (MR) and Octanol/water Partition Coefficient (LogP) of barbiturates is studied. The chemical structures of the molecules were optimized using ab initio 6-31G basis set method and Polak-Ribiere algorithm with conjugated gradient within HyperChem 8.0 environ...

Intravenous Anæsthesia

Architecture Design Utilizing Precedents The Study of How Iranian Professional Architects Use Design Precedents

Designers usually use precedents in their designs. They may use them through different stages of the design process and to different ends. As this use is important, the study of its positive and negative aspects has encouraged numerous studies to find out about the correct way of using them. In this paper, the use of design precedents is studied by interviewing professional architects and the r...

SYNTHESIS OF NEW PHASE- 1 METABOLITES OF TWO BARBITURATES

The new 4'- hydroxy and 3'- aldehyde phase- 1 metabolites of butobarbitone and pentobarbitone are fully synthesized for the first time. These metabolites were used to idenfity and quantify the natural metabolites in human urine after single and multiple doses of these drugs. The synthesized metobolites have spectral characterizations (IR, NMR, U.V. and mass spectroscopy) consisted with the ...